Stimulants

Route

Snorted, smoked, injected

Effects

Euphoria, energy, hyperactivity, tachycardia High dose: paranoia, irritability, formication

Physical
Mechanism of Action
Street names

Coke, blow, base, crack

Cost

Eight ball: 1/8 ounce of cocaine: $100-200

  • Crack cocaine is pure cocaine vapour that goes directly from your lungs, which have lots of surface area, and directly to your brain (no first pass metabolism), and it is short acting, which makes them highly addictive
  • If you tried to smoke cocaine powder, it would just melt, it would be like smoking sugar
Difference compared to regular cocaine

Normal cocaine has a hydrochloride, and a high melting point, making it hard to smoke. Crack cocaine is created as a result of mixing cocaine with a base (ammonia, NaHCO3). This technique is called freebasing, and allows it so sublimate at lower temperatures so it can be smoked. Compared to cocaine, it is easier to use and has a faster onset.

Cost

Cheap ($20 per rock)

Also known as 3,4-Methylenedioxymethamphetamine

Effects
  • Openness, empathy, energy, euphoria, and well-being
Physical
  • Pupil dilation, enhanced color perception. Restlessness, decreased appetite, altered focus / concentration. Dyspnea, paresthesia, hyperhydrosis, tachycardia. High doses: facial dystonia (“gurning”)
Mechanism of Action
  • Release and re-uptake inhibition of serotonin, dopamine and norepinepherine
  • Binds to 5-HT2A and alpha2 receptors
Street names
  • E, xtc, x:
Cost
  • $10-20 per pill
Route

po, iv

Effects

Euphoria, increased energy, alertness, decreased appetite High doses: paranoia, dystonia, aggression, cardiac arrhythmias

Physical
Mechanism of Action
Street names

Speed

Cost

Also known as Crystal meth, or N-methylamphetamine

Route

Smoked, injected, oral

Effects
Physical
Mechanism of Action

Catecholamine release Also inhibits reuptake

Street names

ice, crystal meth, crystal, crank

Cost

1/8 ounce: $50

For Patients

For Providers

Research