Magnetic Seizure Therapy (MST) is a form of brain stimulation performed under general anesthesia, where electromagnetic induction to is used to induce an electric field in the brain strong enough to elicit a generalized tonic-clonic seizure. MST is currently an investigative therapy, and being explored as an alternative to ECT.
Neurostimulation | Overall Recommendation | Acute Efficacy | Maintenance Efficacy | Safety and Tolerability |
---|---|---|---|---|
rTMS | • First line (for patients who have failed at least 1 antidepressant) | Level 1 | Level 3 | Level 1 |
ECT | • Second line • First line in some acute clinical situations | Level 1 | Level 1 | Level 1 |
tDCS | • Third line | Level 2 | Level 3 | Level 2 |
Vagal Nerve Stimulation (VNS) | • Third line | Level 3 | Level 2 | Level 2 |
DBS | • Investigational | Level 3 | Level 3 | Level 3 |
MST | • Investigational | Level 3 | Not known | Level 3 |