Systemic Lupus Erythematosus (SLE) can prevent with significant neuropsychiatric symptoms include depression and psychosis.[1]
A comprehensive review of systems should be done, including asking about rashes, skin changes other than acne, ulcers, joint pain, joint swelling, hair loss, dry eyes, dry mouth, muscle pain, cardiovascular and respiratory symptoms. Other autoimmune symptoms include Raynaud's syndrome/phenomenon (fingers turning white in the cold).