Deprescribing (or tapering) benzodiazepines is an important clinical skill. While there may be some indication for long-term use of benzodiazepines for certain individuals, most individuals on benzodiazepines do not need to be on it long-term! Studies showing the long-term efficacy of benzodiazepines are lacking. When tapering benzodiazepines, consider the duration of treatment, the dose, and the half-life of the benzodiazepine. If the patient has been on the benzodiazepine for more than 12 weeks, one may want to taper at a rate of 10 to 25% per week. Towards the later part of the taper, the taper should be slowed down more.
Some individuals on benzodiazepines for prolonged periods of time may meet criteria for a benzodiazepine use disorder. It is thus important to ask about other benzodiazepine or sedative hypnotic use (prescribed, non-prescribed, recreational), and other substance use.
Several jurisdictions and organizations have published recommendations on how to switch/taper benzodiazepines.
Deprescribing.org[1] | World Health Organization | San Francisco Health Plan | |
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Jurisdiction | Canada | WHO | US |
Link | Download | WHO Clinical Guidelines (2009) | Download |
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week between dose reductions).Withdrawal management alone is unlikely to lead to sustained abstinence from benzodiazepines. Psychosocial treatment is just as important! If patients were on a benzodiazepine for an underlying psychiatric disorder, these psychiatric disorders must also be treated, or the risk of benzodiazepine use will be extremely high again.