January 2020 By PsychDB.com

Cannabis Use Disorder

Cannabis Use Disorder is a substance use disorder characterized by a problematic pattern of cannabis (marijuana) use leading to clinically significant impairment or distress. Like with all substance use disorders, there is a complex interplay between biological, social, psychological, and cultural factors.

Cannabis (marijuana) is a genus of flowering plant in the family Cannabaceae. ∆9-tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis.

Street names

Pot, weed, herb, ganga

Effects

Euphoria, dry-mouth, dilated pupils, giddiness, hunger, anti-nausea, paranoia, cognitive impairment

Routes

Smoked, oral

Mechanism of Action

  • ∆9-tetrahydrocannabinol
  • Agonists at cannabinoid receptors CB1, CB2: GPCR
  • CNS, peripheral and immune system expression
Cost

$40 per 1/8 ounce

The link between cannabis use and psychosis is controversial. However, there is increasing evidence to suggest a link between cannabis use and it's effect on accelerating the onset of schizophrenia in vulnerable individuals. This is especially true with cannabis use during puberty.[1] Whether it is a true cause-and-effect remains under investigation.

Focus on psychosocial management over medical treatment