- Last edited on January 18, 2024
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brain-stimulation:mst [on January 18, 2024] psychdb [Effectiveness] |
brain-stimulation:mst [on January 18, 2024] psychdb [Effectiveness] |
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| * Early studies comparing ECT with MST have found similar rates of improvement of major depressive disorder. There are no studies of depressive relapse following MST or of relapse prevention strategies using MST. As a result, MST continues to be recommended as an investigational treatment.[([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994792/|Milev, R. V., Giacobbe, P., Kennedy, S. H., Blumberger, D. M., Daskalakis, Z. J., Downar, J., ... & CANMAT Depression Work Group. (2016). Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 4. Neurostimulation treatments. The Canadian Journal of Psychiatry, 61(9), 561-575.]])] | * Early studies comparing ECT with MST have found similar rates of improvement of major depressive disorder. There are no studies of depressive relapse following MST or of relapse prevention strategies using MST. As a result, MST continues to be recommended as an investigational treatment.[([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994792/|Milev, R. V., Giacobbe, P., Kennedy, S. H., Blumberger, D. M., Daskalakis, Z. J., Downar, J., ... & CANMAT Depression Work Group. (2016). Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 4. Neurostimulation treatments. The Canadian Journal of Psychiatry, 61(9), 561-575.]])] | ||
| * A recent randomized clinical trial found no significant difference in response or remission rates between MST and ultrabrief pulse right unilateral (RUL) ECT in the treatment of major depressive disorder.[([[https://pubmed.ncbi.nlm.nih.gov/38055283/|Deng, Z. D., Luber, B., McClintock, S. M., Weiner, R. D., Husain, M. M., & Lisanby, S. H. (2023). Clinical Outcomes of Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode: A Randomized Clinical Trial. JAMA psychiatry.]])] | * A recent randomized clinical trial found no significant difference in response or remission rates between MST and ultrabrief pulse right unilateral (RUL) ECT in the treatment of major depressive disorder.[([[https://pubmed.ncbi.nlm.nih.gov/38055283/|Deng, Z. D., Luber, B., McClintock, S. M., Weiner, R. D., Husain, M. M., & Lisanby, S. H. (2023). Clinical Outcomes of Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode: A Randomized Clinical Trial. JAMA psychiatry.]])] | ||
| + | * Note that this finding does not mean the two treatments are similar in efficacy.[([[https://davidgratzer.com/reading-of-the-week/reading-of-the-week-clozapine-neutropenia-the-new-lancet-psych-paper-also-a-letter-to-the-editor-and-bialik-on-mental-health/|Letter to the Editor: Re: “Clinical Outcomes of Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode: A Randomized Clinical Trial” - Reading of the Week]])] | ||
| ===== Side Effects ===== | ===== Side Effects ===== | ||