- Last edited on March 4, 2021
Differences
This shows you the differences between two versions of the page.
child:genetic-disorders:digeorge-syndrome-22q11.2-22q-deletion [on April 12, 2019] |
child:genetic-disorders:digeorge-syndrome-22q11.2-22q-deletion [on April 17, 2019] |
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<callout type="danger" title="Antipsychotics Can Mask Early-Onset Parkinson's Symptoms in DiGeorge + Schizophrenia Patients" icon="true"> | <callout type="danger" title="Antipsychotics Can Mask Early-Onset Parkinson's Symptoms in DiGeorge + Schizophrenia Patients" icon="true"> | ||
- | Individuals with DiGeorge have a higher risk for early-onset [[geri:parkinsons|Parkinson's Disease]].[([[https://www.ncbi.nlm.nih.gov/pubmed/24018986|Butcher, N. J., Kiehl, T. R., Hazrati, L. N., Chow, E. W., Rogaeva, E., Lang, A. E., & Bassett, A. S. (2013). Association between early-onset Parkinson disease and 22q11. 2 deletion syndrome: identification of a novel genetic form of Parkinson disease and its clinical implications. JAMA neurology, 70(11), 1359-1366.]])] As a result, individuals with concomitant schizophrenia and on long-term antipsychotic treatment may have their emerging Parkinson's symptoms masked and mistakenly attributed as [[meds:side-effects:eps|extrapyramidal symptoms]]. | + | Individuals with DiGeorge have a higher risk for early-onset [[geri:parkinsons|Parkinson's Disease]].[([[https://www.ncbi.nlm.nih.gov/pubmed/24018986|Butcher, N. J., Kiehl, T. R., Hazrati, L. N., Chow, E. W., Rogaeva, E., Lang, A. E., & Bassett, A. S. (2013). Association between early-onset Parkinson disease and 22q11. 2 deletion syndrome: identification of a novel genetic form of Parkinson disease and its clinical implications. JAMA neurology, 70(11), 1359-1366.]])] As a result, individuals with concomitant schizophrenia and on long-term antipsychotic treatment may have their emerging Parkinson's symptoms masked and mistakenly attributed as [[meds:antipsychotics:eps|extrapyramidal symptoms]]. |
</callout> | </callout> | ||
===== Pathophysiology ===== | ===== Pathophysiology ===== |