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child:genetic-disorders:down-syndrome-trisomy-21 [on April 11, 2019]
child:genetic-disorders:down-syndrome-trisomy-21 [on April 12, 2019]
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-{{INLINETOC}} 
 ====== Down Syndrome (Trisomy 21) ====== ====== Down Syndrome (Trisomy 21) ======
 +{{INLINETOC}}
 ===== Primer ===== ===== Primer =====
 **Down Syndrome** (Trisomy 21) is the most common identifiable genetic cause of [[child:​intellectual-disability:​home|intellectual disability]]. It is due to the presence of all or part of a third copy of chromosome 21. Individuals with Down syndrome have a characteristic facial appearance and hypotonia in infancy. About half are born with a heart defect. **Down Syndrome** (Trisomy 21) is the most common identifiable genetic cause of [[child:​intellectual-disability:​home|intellectual disability]]. It is due to the presence of all or part of a third copy of chromosome 21. Individuals with Down syndrome have a characteristic facial appearance and hypotonia in infancy. About half are born with a heart defect.