- Last edited on July 18, 2023
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cl:0-autoimmune-encephalitis:hashimotos [on August 26, 2019] |
cl:0-autoimmune-encephalitis:hashimotos [on August 26, 2019] |
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| The clinical presentation of HE can include seizures, myoclonus, hallucinations, and stroke-like episodes with normal or non-specific CSF and brain MRI abnormalities. | The clinical presentation of HE can include seizures, myoclonus, hallucinations, and stroke-like episodes with normal or non-specific CSF and brain MRI abnormalities. | ||
| </callout> | </callout> | ||
| + | <callout type="question" title="Controversial Diagnosis" icon="true"> | ||
| + | Hashimoto’s encephalopathy should be diagnosed only when a thorough clinical assessment has been performed, including comprehensive testing for well characterized neuronal antibodies, and ruling out other potential causes of encephalopathy or encephalitis. In essence, it should be a diagnosis of exclusion.</callout> | ||
| </WRAP> | </WRAP> | ||
| </WRAP> | </WRAP> | ||
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| </WRAP> | </WRAP> | ||
| <WRAP half column> | <WRAP half column> | ||
| - | <callout type="warning" title="Antibodies Are Non-Specific!" icon="true"> | + | <callout type="warning" title="Thyroid Antibodies Are Non-Specific!" icon="true"> |
| Thyroid antibodies are not specific for Hashimoto’s encephalopathy. They can be present in up to 13% of healthy individuals, and up to 27% in white women older than 60 years. It can also be present in other autoimmune encephalitis disorders. | Thyroid antibodies are not specific for Hashimoto’s encephalopathy. They can be present in up to 13% of healthy individuals, and up to 27% in white women older than 60 years. It can also be present in other autoimmune encephalitis disorders. | ||
| </callout> | </callout> | ||