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cl:2-major-neurocog-disorder [on March 20, 2019]
 cl:2-major-neurocog-disorder [on September 13, 2020]
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-~~NOTOC~~ 
 ====== Major Neurocognitive Disorder ====== ====== Major Neurocognitive Disorder ======
 +{{INLINETOC}}
 +
 +===== Primer =====
 +
 +== Epidemiology ==
 +The dementia subtypes contributing to major neurocognitive disorder is estimated to be 31.3% [[geri:​dementia:​alzheimers|Alzheimer'​s dementia]], 21.9% [[geri:​dementia:​vascular|vascular dementia]], 10.9% [[geri:​dementia:​lewy-body|Lewy body dementia]], and 7.8% [[geri:​dementia:​frontotemporal|frontotemporal dementia]].[([[https://​pubmed.ncbi.nlm.nih.gov/​11872521/​|Stevens,​ T. I. M., Livingston, G., Kitchen, G., Manela, M., Walker, Z., & Katona, C. (2002). Islington study of dementia subtypes in the community. The British Journal of Psychiatry, 180(3), 270-276.]])]
 +
 +== Prognosis ==
 +
 +== Comorbidity ==
 +
 +== Risk Factors ==
  
 ===== Diagnostic Criteria ===== ===== Diagnostic Criteria =====
 <WRAP group> <WRAP group>
 <WRAP half column> <WRAP half column>
-==== Criterion A ==== +== Criterion A == 
-Evidence of **//​significant//​** cognitive decline from a previous level of performance in one or more cognitive domains (complex attention, executive function, learning and memory, language, perceptual-motor,​ or social cognition) based on:+Evidence of **//​significant//​** cognitive decline from a previous level of performance in ''​1'' ​or more cognitive domains (complex attention, executive function, learning and memory, language, perceptual-motor,​ or social cognition) based on:
   - Concern of the individual, a knowledgeable informant, or the clinician that there has been a significant decline in cognitive function; and   - Concern of the individual, a knowledgeable informant, or the clinician that there has been a significant decline in cognitive function; and
   - A substantial impairment in cognitive performance,​ preferably documented by standardized neuropsychological testing or, in its absence, another quantified clinical assessment.   - A substantial impairment in cognitive performance,​ preferably documented by standardized neuropsychological testing or, in its absence, another quantified clinical assessment.
  
-==== Criterion B ====+== Criterion B ==
 The cognitive deficits **//​interfere with independence in everyday activities//​** (i.e., at a minimum, requiring assistance with complex instrumental activities of daily living such as paying bills or managing medications). The cognitive deficits **//​interfere with independence in everyday activities//​** (i.e., at a minimum, requiring assistance with complex instrumental activities of daily living such as paying bills or managing medications).
  
-==== Criterion C ====+== Criterion C ==
 The cognitive deficits do not occur exclusively in the context of a delirium. The cognitive deficits do not occur exclusively in the context of a delirium.
  
-==== Criterion D ====+== Criterion D ==
 The cognitive deficits are not better explained by another mental disorder (e.g., [[mood:​1-depression:​home|major depressive disorder]], [[psychosis:​schizophrenia-scz|schizophrenia]]). The cognitive deficits are not better explained by another mental disorder (e.g., [[mood:​1-depression:​home|major depressive disorder]], [[psychosis:​schizophrenia-scz|schizophrenia]]).
 </​WRAP>​ </​WRAP>​