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cl:hepatic-encephalopathy [on July 23, 2020] (current)
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 +====== Hepatic Encephalopathy ======
 +===== Primer =====
 +**Hepatic encephalopathy (HE)** or **Portosystemic Encephalopathy (PSE)** is a neuropsychiatric syndrome that can develop in patients with liver disease.
 +
 +==== Symptoms ====
 +Cognitive impairment, altered level of consciousness,​ ataxia.
 +==== Investigations ====
 +  * Ammonia levels
 +  * Abdominal ultrasound
 +  * EEGs (to look for findings of encephalopathy)
 +
 +==== Differential Diagnosis ====
 +  * **[[meds:​mood-stabilizers-anticonvulsants:​1-valproic-divalproex#​hyperammonemic-encephalopathy|Valproate-induced hyperammonemic encephalopathy (VHE)]]**
 +===== Resources =====
 +==== Literature ====
 +  * [[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC5421503/​|Ferenci,​ P. (2017). Hepatic encephalopathy. Gastroenterology report, 5(2), 138-147.]]
 +  * [[https://​pubmed.ncbi.nlm.nih.gov/​10206828/​|Wiltfang,​ J., Nolte, W., Weissenborn,​ K., Kornhuber, J., & Rüther, E. (1998). Psychiatric aspects of portal-systemic encephalopathy. Metabolic brain disease, 13(4), 379-389.]]
 +  * [[https://​pubmed.ncbi.nlm.nih.gov/​24365345/​|Weissenborn K. (2014). Portosystemic encephalopathy. Handbook of clinical neurology, 120, 661–674.]]
 +  * [[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC6159236/​|Tomiyama,​ A., Oguro, S., Kato, M., Watanabe, H., Yamazaki, H., Suzuki, T., & Tominaga, S. (2016). Successful embolisation of intrahepatic portosystemic venous shunt using AMPLATZER Vascular Plug II. BJR| case reports, 20160061.]]
 +  * [[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3484308/​|Lee,​ Y. J., Shin, B. S., Lee, I. H., Ohm, J. Y., Lee, B. S., Ahn, M., & Kim, H. J. (2012). Intrahepatic portosystemic venous shunt: successful embolization using the Amplatzer Vascular Plug II. Korean journal of radiology, 13(6), 827-831.]]