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cl:moyamoya-disease [on August 26, 2019]
 cl:moyamoya-disease [on August 26, 2019]
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 Depression or anxiety in assessment of new focal neurological symptoms is more common. Transient ischemic attacks may be mistaken for anxiety and panic disorder. Psychiatric symptoms in moyamoya disease is heterogeneous,​ and affects up to 25% of patients. In adults, refractory depression and psychosis with new focal neurological deficits may be signs of moyamoya.[([[https://​www.ncbi.nlm.nih.gov/​pubmed/​21290161|Lee,​ K. O., & Lee, K. Y. (2011). Fluctuating frontal lobe dysfunction in a patient with moyamoya disease. Neurological Sciences, 32(4), 743-746.]])] Depression or anxiety in assessment of new focal neurological symptoms is more common. Transient ischemic attacks may be mistaken for anxiety and panic disorder. Psychiatric symptoms in moyamoya disease is heterogeneous,​ and affects up to 25% of patients. In adults, refractory depression and psychosis with new focal neurological deficits may be signs of moyamoya.[([[https://​www.ncbi.nlm.nih.gov/​pubmed/​21290161|Lee,​ K. O., & Lee, K. Y. (2011). Fluctuating frontal lobe dysfunction in a patient with moyamoya disease. Neurological Sciences, 32(4), 743-746.]])]
 ===== Investigations ===== ===== Investigations =====
 +==== MRI ====
 +Brain MRI with contrast, T2-weighted fluid-attenuated inversion recovery (FLAIR) may have hyperintense signals and new ischemic changes.
 +
 +==== Angiograms ====
 Diagnostic cerebral angiograms will reveal fragile compensatory collateral vessels forming along the base of the brain, these fragile vessels resemble the diagnostic “puff of smoke,” hence the term moyamoya (もやもや) in Japanese. Diagnostic cerebral angiograms will reveal fragile compensatory collateral vessels forming along the base of the brain, these fragile vessels resemble the diagnostic “puff of smoke,” hence the term moyamoya (もやもや) in Japanese.
 ===== Treatment ===== ===== Treatment =====