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geri:dementia:alzheimers [on February 9, 2024]
psychdb [Deprescribing]
geri:dementia:alzheimers [on February 9, 2024]
psychdb [Depression]
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 ==== Depression ==== ==== Depression ====
   * For depressive symptoms, if a patient had an inadequate response to the nonpharmacological interventions or has a major affective disorder, severe dysthymia or severe emotional lability, a trial of an [[meds:​antidepressants:​home|antidepressant]] //could// be considered.[([[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3980908/​|Herrmann,​ N., Lanctôt, K. L., & Hogan, D. B. (2013). Pharmacological recommendations for the symptomatic treatment of dementia: the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012. Alzheimer'​s research & therapy, 5(1), S5.]])]   * For depressive symptoms, if a patient had an inadequate response to the nonpharmacological interventions or has a major affective disorder, severe dysthymia or severe emotional lability, a trial of an [[meds:​antidepressants:​home|antidepressant]] //could// be considered.[([[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3980908/​|Herrmann,​ N., Lanctôt, K. L., & Hogan, D. B. (2013). Pharmacological recommendations for the symptomatic treatment of dementia: the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012. Alzheimer'​s research & therapy, 5(1), S5.]])]
-  * However, the response rates are low.+  * However, the response rates are low and possibly lower than non-pharmacological interventions.[([[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC7988455/​|Watt,​ J. A., Goodarzi, Z., Veroniki, A. A., Nincic, V., Khan, P. A., Ghassemi, M., ... & Straus, S. E. (2021). Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis. bmj, 372.]])]
  
 ==== Deprescribing ==== ==== Deprescribing ====