- Last edited on February 9, 2024
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geri:dementia:alzheimers [on February 9, 2024] psychdb [Deprescribing] |
geri:dementia:alzheimers [on February 9, 2024] psychdb [Depression] |
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==== Depression ==== | ==== Depression ==== | ||
* For depressive symptoms, if a patient had an inadequate response to the nonpharmacological interventions or has a major affective disorder, severe dysthymia or severe emotional lability, a trial of an [[meds:antidepressants:home|antidepressant]] //could// be considered.[([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980908/|Herrmann, N., Lanctôt, K. L., & Hogan, D. B. (2013). Pharmacological recommendations for the symptomatic treatment of dementia: the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012. Alzheimer's research & therapy, 5(1), S5.]])] | * For depressive symptoms, if a patient had an inadequate response to the nonpharmacological interventions or has a major affective disorder, severe dysthymia or severe emotional lability, a trial of an [[meds:antidepressants:home|antidepressant]] //could// be considered.[([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980908/|Herrmann, N., Lanctôt, K. L., & Hogan, D. B. (2013). Pharmacological recommendations for the symptomatic treatment of dementia: the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012. Alzheimer's research & therapy, 5(1), S5.]])] | ||
- | * However, the response rates are low. | + | * However, the response rates are low and possibly lower than non-pharmacological interventions.[([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988455/|Watt, J. A., Goodarzi, Z., Veroniki, A. A., Nincic, V., Khan, P. A., Ghassemi, M., ... & Straus, S. E. (2021). Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis. bmj, 372.]])] |
==== Deprescribing ==== | ==== Deprescribing ==== |