- Last edited on February 5, 2024
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geri:dementia:lewy-body [on April 17, 2019] |
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====== Lewy Body Dementia (LBD) ====== | ====== Lewy Body Dementia (LBD) ====== | ||
+ | {{INLINETOC}} | ||
===== Primer ===== | ===== Primer ===== | ||
**Lewy Body Dementia/Disease** (LBD) also known as **Dementia with Lewy Bodies** (DLB), is a neurodegenerative disorder associated with abnormal deposits of a protein called alpha-synuclein in the brain. It is characterized by progressive cognitive impairment (with early changes in complex attention and executive function rather than learning and memory), recurrent complex visual hallucinations, rapid eye movement (REM) sleep behavior disorder, depression, and/or delusions. LBD is one of the most common causes of dementia. | **Lewy Body Dementia/Disease** (LBD) also known as **Dementia with Lewy Bodies** (DLB), is a neurodegenerative disorder associated with abnormal deposits of a protein called alpha-synuclein in the brain. It is characterized by progressive cognitive impairment (with early changes in complex attention and executive function rather than learning and memory), recurrent complex visual hallucinations, rapid eye movement (REM) sleep behavior disorder, depression, and/or delusions. LBD is one of the most common causes of dementia. | ||
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==== Neuroimaging ==== | ==== Neuroimaging ==== | ||
- | A diagnostically suggestive feature is low striatal dopamine transporter uptake on [[neurology:investigations:neuroimaging:spect|]] or positron emission tomography (PET) scan. See also: [[https://ebmh.bmj.com/content/21/2/61|Surendranathan, A., & O’brien, J. T. (2018). Clinical imaging in dementia with Lewy bodies. Evidence-based mental health, 21(2), 61-65.]] | + | A diagnostically suggestive feature is low striatal dopamine transporter uptake on [[neurology:spect]] or positron emission tomography (PET) scan. See also: [[https://ebmh.bmj.com/content/21/2/61|Surendranathan, A., & O’brien, J. T. (2018). Clinical imaging in dementia with Lewy bodies. Evidence-based mental health, 21(2), 61-65.]] |
==== Antipsychotics ==== | ==== Antipsychotics ==== |