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geri:dementia:lewy-body [on February 5, 2024]
psychdb [Neuroimaging]
geri:dementia:lewy-body [on February 5, 2024]
psychdb [Neuroimaging]
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   * Different types of [[neurology:​spect|brain perfusion scans (SPECT)]] can be done:​[([[https://​ebmh.bmj.com/​content/​21/​2/​61|Surendranathan,​ A. et al. (2018). Clinical imaging in dementia with Lewy bodies. Evidence-based mental health, 21(2), 61-65.]])]   * Different types of [[neurology:​spect|brain perfusion scans (SPECT)]] can be done:​[([[https://​ebmh.bmj.com/​content/​21/​2/​61|Surendranathan,​ A. et al. (2018). Clinical imaging in dementia with Lewy bodies. Evidence-based mental health, 21(2), 61-65.]])]
     * **<​sup>​123</​sup>​Iodine-metaiodobenzylguanidine myocardial scintigraphy (MIBG)** may show low striatal dopamine transporter uptake     * **<​sup>​123</​sup>​Iodine-metaiodobenzylguanidine myocardial scintigraphy (MIBG)** may show low striatal dopamine transporter uptake
-    * **<​sup>​123</​sup>​I-ioflupane single-photon emission computed tomography (SPECT)** ​or dopamine transporter (DAT) scans+    * **<​sup>​123</​sup>​I-ioflupane single-photon emission computed tomography (SPECT)**, also known as a **dopamine transporter (DAT) scan**
       * This assesses DAT uptake in the basal ganglia in vivo, and has been shown to be more specific than clinical diagnostic criteria for DLB.       * This assesses DAT uptake in the basal ganglia in vivo, and has been shown to be more specific than clinical diagnostic criteria for DLB.
       * It maybe the most reliable imaging modality of choice in differentiating DLB from pure AD.       * It maybe the most reliable imaging modality of choice in differentiating DLB from pure AD.