- Last edited on November 24, 2021
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geri:dementia:primary-progressive-aphasia-ppa [on September 16, 2018] |
geri:dementia:primary-progressive-aphasia-ppa [on June 2, 2019] |
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+ | ====== Primary Progressive Aphasia (PPA) ====== | ||
+ | ===== Primer ===== | ||
+ | **Primary Progressive Aphasia (PPA)** is a neurological syndrome associated with certain types of dementia. [[geri:dementia:alzheimers|Alzheimer’s Disease]] and [[geri:dementia:frontotemporal|frontotemporal dementia]] are the most common underlying forms of dementia in which PPA occurs. PPA typically begins as gradual, subtle language deficits that progresses to a nearly complete inability to speak. | ||
+ | |||
+ | ==== Variants ==== | ||
+ | There are three variants of PPA: | ||
+ | - Semantic (the dominant type and is present in most instances of PPA) | ||
+ | - Logopenic (LPA), due to atrophy in the left posterior temporal cortex and inferior parietal lobule | ||
+ | - Non-fluent/agrammatic (stumbling for words, grammar is very poor) | ||
+ | |||
+ | ===== Diagnostic Criteria ===== | ||
+ | * [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059138/|Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. E. E. A., ... & Manes, F. (2011). Classification of primary progressive aphasia and its variants. Neurology, WNL-0b013e31821103e6.]] | ||