June 2019 By PsychDB.com

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geri:dementia:primary-progressive-aphasia-ppa [September 2018]
PsychDB.com [Variants]
geri:dementia:primary-progressive-aphasia-ppa [June 2019] (current)
PsychDB.com ↷ Page name changed from geri:dementia:ppa to geri:dementia:primary-progressive-aphasia-ppa
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 +====== Primary Progressive Aphasia (PPA) ======
 +===== Primer =====
 +**Primary Progressive Aphasia (PPA)** is a neurological syndrome associated with certain types of dementia. [[geri:​dementia:​alzheimers|Alzheimer’s Disease]] and [[geri:​dementia:​frontotemporal|frontotemporal dementia]] are the most common underlying forms of dementia in which PPA occurs. PPA typically begins as gradual, subtle language deficits that progresses to a nearly complete inability to speak.
 +
 +==== Variants ====
 +There are three variants of PPA:
 +  - Semantic (the dominant type and is present in most instances of PPA)
 +  - Logopenic (LPA), due to atrophy in the left posterior temporal cortex and inferior parietal lobule
 +  - Non-fluent/​agrammatic (stumbling for words, grammar is very poor)
 +
 +===== Diagnostic Criteria =====
 +  * [[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3059138/​|Gorno-Tempini,​ M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. E. E. A., ... & Manes, F. (2011). Classification of primary progressive aphasia and its variants. Neurology, WNL-0b013e31821103e6.]]