- Last edited on January 25, 2022
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meds:agitation [on December 17, 2019] |
meds:agitation [on September 14, 2020] |
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====== Pharmacological Management of Acute Agitation ====== | ====== Pharmacological Management of Acute Agitation ====== | ||
{{INLINETOC}} | {{INLINETOC}} | ||
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<panel type="info" title="Haloperidol versus Loxapine" subtitle="Adapted from Procyshyn, Ric M., Kalyna Z. Bezchlibnyk-Butler, and J. Joel Jeffries. Clinical Handbook of Psychotropic Drugs. Hogrefe, 2017." no-body="true"> | <panel type="info" title="Haloperidol versus Loxapine" subtitle="Adapted from Procyshyn, Ric M., Kalyna Z. Bezchlibnyk-Butler, and J. Joel Jeffries. Clinical Handbook of Psychotropic Drugs. Hogrefe, 2017." no-body="true"> | ||
- | !^! ^ Description ^ Haloperidol ^ Loxapine ^ | + | <mobiletable 1> |
+ | ^ ^ Description ^ Haloperidol ^ Loxapine ^ | ||
^ Potency | The amount of medication that needs to be given | High | Intermediate | | ^ Potency | The amount of medication that needs to be given | High | Intermediate | | ||
^ D2 Antagonism | Amount of antipsychotic effect, and EPS risk | +++++ | ++++ | | ^ D2 Antagonism | Amount of antipsychotic effect, and EPS risk | +++++ | ++++ | | ||
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^ 5-HT2 Antagonism | Amount of anxiolytic effect/sedation | +/+++ | +++/++++ | | ^ 5-HT2 Antagonism | Amount of anxiolytic effect/sedation | +/+++ | +++/++++ | | ||
^ ACh M1 Antagonism | Mitigation of EPS, sedation | + | ++ | | ^ ACh M1 Antagonism | Mitigation of EPS, sedation | + | ++ | | ||
+ | </mobiletable> | ||
</panel> | </panel> | ||
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* [[https://www.psychiatryadvisor.com/home/opinion/haloperidol-in-the-emergency-department-setting/|PsychiatryAdvisor: Haloperidol in the Emergency Department Setting]] | * [[https://www.psychiatryadvisor.com/home/opinion/haloperidol-in-the-emergency-department-setting/|PsychiatryAdvisor: Haloperidol in the Emergency Department Setting]] | ||
+ | {{tag>rx}} | ||