- Last edited on October 10, 2023
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meds:antipsychotics:home [on May 18, 2020] |
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- | Antipsychotic function can best be understood by their degree of affinity for the dopamine receptor, or potency (i.e. - "how much of the drug you need to produce a clinical effect?").[([[https://www.biomedcentral.com/1471-244x/9/24/table/t1|Table 1: Antipsychotic equivalent doses and Defined Daily Doses of common antipsychotics.]])][([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693495/pdf/1471-244X-9-24.pdf|Kroken, Rune A et al. Treatment of Schizophrenia with Antipsychotics in Norwegian Emergency Wards, a Cross-Sectional National Study. BMC Psychiatry 9 (2009): 24.]])] This can be seen in the actual dose of the antipsychotic itself (for example, the therapeutic dose of risperidone (high potency) is 2-3 mg, whereas quetiapine (low potency) can be up to 800 mg). | + | Antipsychotic function can best be understood by their degree of affinity for the dopamine receptor, or potency (i.e. - "how much of the drug you need to produce a clinical effect?").[([[https://www.biomedcentral.com/1471-244x/9/24/table/t1|Table 1: Antipsychotic equivalent doses and Defined Daily Doses of common antipsychotics.]])][([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693495/pdf/1471-244X-9-24.pdf|Kroken, Rune A et al. Treatment of Schizophrenia with Antipsychotics in Norwegian Emergency Wards, a Cross-Sectional National Study. BMC Psychiatry 9 (2009): 24.]])] This can be seen in the actual dose of the antipsychotic itself (e.g. - the therapeutic dose of risperidone (high potency) is 2-3 mg, whereas quetiapine (low potency) can be up to 800 mg). |
* **High potency** (i.e. - you only need to prescribe a "low dose" to get a clinical effect) | * **High potency** (i.e. - you only need to prescribe a "low dose" to get a clinical effect) |