- Last edited on March 6, 2021
Differences
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meds:mood-stabilizers-anticonvulsants:carbamazepine [on May 21, 2019] |
meds:mood-stabilizers-anticonvulsants:carbamazepine [on March 21, 2020] |
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===== Dose ===== | ===== Dose ===== | ||
- | 100-1200mg (using the CR formulation) | + | The dose range for carbamazepine is between 100-1200mg (using the CR formulation), and it is usually dosed BID. Carbamazepine can be increased by 100 mg every 2-3 days as tolerated, up to an initial target dose of at least 300 mg/day. After at least 5 days at this target dose (to allow steady state to be achieve), a carbamazepine level should be drawn 12 hours after the last dose. If the level is: |
+ | * <17 μmol/L, then the dose should be increased by 100 mg/day and another level should be drawn in 5 days | ||
+ | * 17-54 μmol/L, then the dose can be maintained | ||
+ | * >54 μmol/L, then the dose should be reduced by 100 mg/day and another level should be drawn in 5 days | ||
+ | Note that carbamazepine induces its own metabolism thus drawing levels repeatedly for the same dose will be necessary over the first few weeks, making dose adjustments as necessary. | ||
==== Monitoring ==== | ==== Monitoring ==== |