- Last edited on January 26, 2022
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mood:1-depression:psychotic [on September 10, 2018] |
mood:1-depression:psychotic [on May 21, 2019] |
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+ | ====== Psychotic Depression ====== | ||
+ | {{INLINETOC}} | ||
+ | ===== Primer ===== | ||
+ | **Psychotic Depression** (depression with psychotic features) requires the treatment of the underlying mood disorder. | ||
+ | ===== Differential Diagnosis ===== | ||
+ | * [[https://www.ncbi.nlm.nih.gov/pubmed/28709381|Perera, J. K., Rosenblat, J. D., & Flint, A. J. (2017). Dementia with Lewy bodies presenting as psychotic depression. Australian & New Zealand Journal of Psychiatry, 51(11), 1160-1161.]] | ||
+ | |||
+ | ===== Treatment ===== | ||
+ | Treatment with olanzapine plus sertraline has been shown to be efficacious.[([[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840400/|Meyers, B. S., Flint, A. J., Rothschild, A. J., Mulsant, B. H., Whyte, E. M., Peasley-Miklus, C., ... & Heo, M. (2009). A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD). Archives of general psychiatry, 66(8), 838-847.]])] | ||
+ | |||
+ | * [[https://www.ncbi.nlm.nih.gov/pubmed/28445632|Bingham, K. S., Rothschild, A. J., Mulsant, B. H., Whyte, E. M., Meyers, B. S., Banerjee, S., ... & Flint, A. J. (2017). The Association of Baseline Suicidality With Treatment Outcome in Psychotic Depression. The Journal of clinical psychiatry, 78(8), 1149-1154.]] | ||
+ | * [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686458/|Rothschild, A. J. (2013). Challenges in the treatment of major depressive disorder with psychotic features. Schizophrenia bulletin, 39(4), 787-796.]] |