- Last edited on April 30, 2020
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Psychotic Depression
Primer
Psychotic Depression (depression with psychotic features) requires the treatment of the underlying mood disorder.
Differential Diagnosis
Treatment
Treatment with olanzapine plus sertraline has been shown to be efficacious.[1]
References
1)
Meyers, B. S., Flint, A. J., Rothschild, A. J., Mulsant, B. H., Whyte, E. M., Peasley-Miklus, C., ... & Heo, M. (2009). A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD). Archives of general psychiatry, 66(8), 838-847.