- Last edited on July 7, 2022
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sleep:4-narcolepsy [on July 7, 2022] psychdb |
sleep:4-narcolepsy [on July 7, 2022] (current) psychdb [Narcolepsy Type 2] |
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| ==== Narcolepsy Type 2 ==== | ==== Narcolepsy Type 2 ==== | ||
| - | For Narcolepsy Type 2 (also known as: Hypocretin deficiency syndrome, narcolepsy-cataplexy, narcolepsy with cataplexy), ''Criteria A'' to ''E'' must be met: | + | For Narcolepsy Type 2 (also known as: narcolepsy without cataplexy), ''Criteria A'' to ''E'' must be met: |
| == Criterion A == | == Criterion A == | ||
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| == Criterion C == | == Criterion C == | ||
| - | Cataplexy is absent | + | Cataplexy is absent. |
| == Criterion D == | == Criterion D == | ||
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| == Criterion E == | == Criterion E == | ||
| The hypersomnolence and/or MSLT findings are not better explained by other causes such as insufficient sleep, obstructive sleep apnea, delayed sleep phase disorder, or the effect of medication or substances or their withdrawal. | The hypersomnolence and/or MSLT findings are not better explained by other causes such as insufficient sleep, obstructive sleep apnea, delayed sleep phase disorder, or the effect of medication or substances or their withdrawal. | ||
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| + | <callout title="Notes"> | ||
| + | * If cataplexy develops later, then the disorder should be reclassified as narcolepsy type 1. | ||
| + | * If the CSF Hcrt-1 concentration is tested at a later stage and found to be either ≤ 110 pg/mL or < 1/3 of mean values obtained in normal subjects with the same assay, then the disorder should be reclassified as narcolepsy type 1. | ||
| + | </callout> | ||
| ===== Narcolepsy Type 1 vs. Type 2 ===== | ===== Narcolepsy Type 1 vs. Type 2 ===== | ||