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cl:systemic-lupus-erythematosus [on September 23, 2018]
cl:systemic-lupus-erythematosus [on May 13, 2021] (current)
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 +====== Systemic Lupus Erythematosus (SLE) ======
 +{{INLINETOC}}
 +===== Primer =====
 +**Systemic Lupus Erythematosus** (SLE) can prevent with significant neuropsychiatric symptoms include depression and psychosis.[([[https://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3151599/​|Popescu,​ A., & H Kao, A. (2011). Neuropsychiatric systemic lupus erythematosus. Current neuropharmacology,​ 9(3), 449-457.]])]
  
 +===== Review of Symptoms =====
 +A comprehensive review of systems should be done, including asking about rashes, skin changes other than acne, ulcers, joint pain, joint swelling, hair loss, dry eyes, dry mouth, muscle pain, cardiovascular and respiratory symptoms. Other autoimmune symptoms include Raynaud'​s syndrome/​phenomenon (fingers turning white in the cold).
 +
 +===== Psychosis =====
 +  * [[https://​pubmed.ncbi.nlm.nih.gov/​33629101/​|Abrol,​ E., Coutinho, E., Chou, M., Hart, M., Vincent, A., Howard, R., ... & Isenberg, D. (2021). Psychosis in Systemic Lupus Erythematosus (SLE): 40-year experience of a specialist centre. Rheumatology.]]
 +  * [[https://​www.ncbi.nlm.nih.gov/​pubmed/​22260390|Mantovani,​ C., Louzada‐Junior,​ P., Nunes, E. A., de Figueiredo, F. P., Oliveira, G. R., & Del‐Ben, C. M. (2012). Antinuclear antibodies testing as a routine screening for systemic lupus erythematosus in patients presenting first‐episode psychosis. Early intervention in psychiatry, 6(3), 322-325.]]
 +
 +===== Investigations =====
 +  * ANA
, ESR