The neuropsychiatric symptoms of Systemic Lupus Erythematosus (SLE) are the most prevalent manifestations of lupus.^[1]

A comprehensive review of systems should be done, including asking about rashes, skin changes other than acne, ulcers, joint pain, joint swelling, hair loss, dry eyes, dry mouth, muscle pain, cardiovascular and respiratory symptoms. Other autoimmune symptoms include Raynaud's syndrome/phenomenon (fingers turning white in the cold).

• Mantovani, C., Louzada‐Junior, P., Nunes, E. A., de Figueiredo, F. P., Oliveira, G. R., & Del‐Ben, C. M. (2012). Antinuclear antibodies testing as a routine screening for systemic lupus erythematosus in patients presenting first‐episode psychosis. Early intervention in psychiatry, 6(3), 322-325.

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