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geri:dementia:progressive-supranuclear-palsy-psp [on September 4, 2023]
psychdb [Other Signs]
geri:dementia:progressive-supranuclear-palsy-psp [on September 4, 2023]
psychdb [Other Signs]
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 ==== Other Signs ==== ==== Other Signs ====
-  * The "​Applause sign" may help discriminate PSP from [[geri:​dementia:​frontotemporal|]] and [[geri:​parkinsons|]]. To elicit the sign, patients are asked to clap ''​3''​ times. If they clap more than 3 times, it is a positive sign.+  * The "​Applause sign" may help discriminate PSP from [[geri:​dementia:​frontotemporal|]] and [[geri:​parkinsons|]]. To elicit the sign, patients are asked to clap ''​3''​ times. If they clap more than 3 times, it is a positive sign.[([[https://​pubmed.ncbi.nlm.nih.gov/​15985587/​|Dubois,​ B., Slachevsky, A., Pillon, B., Beato, R., Villalponda,​ J. M., & Litvan, I. (2005). “Applause sign” helps to discriminate PSP from FTD and PD. Neurology, 64(12), 2132-2133.]])]
   * There may also be a so-called "​dirty-tie sign," because individuals cannot see that they are dropping food when they eat.    * There may also be a so-called "​dirty-tie sign," because individuals cannot see that they are dropping food when they eat. 
-  * [([[https://​pubmed.ncbi.nlm.nih.gov/​15985587/​|Dubois,​ B., Slachevsky, A., Pillon, B., Beato, R., Villalponda,​ J. M., & Litvan, I. (2005). “Applause sign” helps to discriminate PSP from FTD and PD. Neurology, 64(12), 2132-2133.]])] 
   * However, more recent studies have suggested that the applause sign should be interpreted as a merely a sign of frontal lobe dysfunction,​ and that it can be found in FTD and AD.[([[https://​pubmed.ncbi.nlm.nih.gov/​21245475/​|Luzzi,​ S., Fabi, K., Pesallaccia,​ M., Silvestrini,​ M., & Provinciali,​ L. (2011). Applause sign: is it really specific for Parkinsonian disorders? Evidence from cortical dementias. Journal of Neurology, Neurosurgery & Psychiatry, 82(8), 830-833.]])]   * However, more recent studies have suggested that the applause sign should be interpreted as a merely a sign of frontal lobe dysfunction,​ and that it can be found in FTD and AD.[([[https://​pubmed.ncbi.nlm.nih.gov/​21245475/​|Luzzi,​ S., Fabi, K., Pesallaccia,​ M., Silvestrini,​ M., & Provinciali,​ L. (2011). Applause sign: is it really specific for Parkinsonian disorders? Evidence from cortical dementias. Journal of Neurology, Neurosurgery & Psychiatry, 82(8), 830-833.]])]