- Last edited on September 4, 2023
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geri:dementia:progressive-supranuclear-palsy-psp [on September 4, 2023] psychdb [Other Signs] |
geri:dementia:progressive-supranuclear-palsy-psp [on September 4, 2023] psychdb [Other Signs] |
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==== Other Signs ==== | ==== Other Signs ==== | ||
- | * The "Applause sign" may help discriminate PSP from [[geri:dementia:frontotemporal|]] and [[geri:parkinsons|]]. To elicit the sign, patients are asked to clap ''3'' times. If they clap more than 3 times, it is a positive sign. | + | * The "Applause sign" may help discriminate PSP from [[geri:dementia:frontotemporal|]] and [[geri:parkinsons|]]. To elicit the sign, patients are asked to clap ''3'' times. If they clap more than 3 times, it is a positive sign.[([[https://pubmed.ncbi.nlm.nih.gov/15985587/|Dubois, B., Slachevsky, A., Pillon, B., Beato, R., Villalponda, J. M., & Litvan, I. (2005). “Applause sign” helps to discriminate PSP from FTD and PD. Neurology, 64(12), 2132-2133.]])] |
* There may also be a so-called "dirty-tie sign," because individuals cannot see that they are dropping food when they eat. | * There may also be a so-called "dirty-tie sign," because individuals cannot see that they are dropping food when they eat. | ||
- | * [([[https://pubmed.ncbi.nlm.nih.gov/15985587/|Dubois, B., Slachevsky, A., Pillon, B., Beato, R., Villalponda, J. M., & Litvan, I. (2005). “Applause sign” helps to discriminate PSP from FTD and PD. Neurology, 64(12), 2132-2133.]])] | ||
* However, more recent studies have suggested that the applause sign should be interpreted as a merely a sign of frontal lobe dysfunction, and that it can be found in FTD and AD.[([[https://pubmed.ncbi.nlm.nih.gov/21245475/|Luzzi, S., Fabi, K., Pesallaccia, M., Silvestrini, M., & Provinciali, L. (2011). Applause sign: is it really specific for Parkinsonian disorders? Evidence from cortical dementias. Journal of Neurology, Neurosurgery & Psychiatry, 82(8), 830-833.]])] | * However, more recent studies have suggested that the applause sign should be interpreted as a merely a sign of frontal lobe dysfunction, and that it can be found in FTD and AD.[([[https://pubmed.ncbi.nlm.nih.gov/21245475/|Luzzi, S., Fabi, K., Pesallaccia, M., Silvestrini, M., & Provinciali, L. (2011). Applause sign: is it really specific for Parkinsonian disorders? Evidence from cortical dementias. Journal of Neurology, Neurosurgery & Psychiatry, 82(8), 830-833.]])] | ||