- Last edited on February 13, 2024
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meds:antidepressants:sexual-dysfunction [on February 13, 2024] psychdb [Resources] |
meds:antidepressants:sexual-dysfunction [on February 13, 2024] psychdb [Primer] |
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| ===== Primer ===== | ===== Primer ===== | ||
| - | **Antidepressant-induced Sexual Dysfunctions** are a very common side effect that is often under-recognized. There are unfortunately few well-designed studies to address this problem, and there are also high placebo-response rates for treatments. | + | **Antidepressant-induced Sexual Dysfunctions** are a very common side effect that is often under-recognized, and for some individuals can be protracted even after antidepressant discontinuation. There are unfortunately few well-designed studies to address this problem, and there are also high placebo-response rates for treatments. |
| ===== Mechanism ===== | ===== Mechanism ===== | ||
| Most antidepressants modulate serotonin, and elevated serotonin levels (via increased stimulation/agonism) are thought to cause sexual dysfunction. Sexual function can be broken down into 3 parts: | Most antidepressants modulate serotonin, and elevated serotonin levels (via increased stimulation/agonism) are thought to cause sexual dysfunction. Sexual function can be broken down into 3 parts: | ||