Table of Contents

Ramelteon (Rozerem)

Primer

Ramelteon (Trade name: Rozerem) is nelatonin receptor agonist use in the treatment of insomnia disorder.

Mnemonic

RaMELteon is a MELatonin receptor agonist.

Pharmacokinetics

Pharmacokinetics of Ramelteon

Ramelteon: Cytochrome P450 Metabolism

Substrate of (Metabolized by)
Induces
Inhibits

Pharmacodynamics

Mechanism of Action

Toxicity

Indications

Dosing

Dosing for Ramelteon

Starting
Titration
Maximum
Taper

Formulations

Monitoring

Contraindications

Absolute

Relative

Drug-Drug Interactions

Side Effects

Adverse Events

Clinical Pearls

Special Populations

Geriatric

Pediatric

Obstetric and Fetal

Medically Ill

Resources