September 2018 By

Niemann-Pick Type C Disease (NPC)

Niemann-Pick type C disease (NPC) is a rare, neurodegenerative, autosomal recessive disease, with an extremely heterogeneous clinical presentation. NPC may initially present in adulthood with psychosis, and when psychosis is associated with a vertical supranuclear gaze palsy, various dyskinesias, and seizures, NPC should be suspected.[1]