Last edited on April 30, 2020 Tryptophan Table of Contents Tryptophan Primer Clinical Pearls Resources Primer Clinical Pearls Tryptophan + SSRIs = Serotonin Syndrome If on long-term therapy, need to also take vitamin D6 to neutralize Resources Richard, D. M., Dawes, M. A., Mathias, C. W., Acheson, A., Hill-Kapturczak, N., & Dougherty, D. M. (2009). L-tryptophan: basic metabolic functions, behavioral research and therapeutic indications. International journal of tryptophan research: IJTR, 2, 45. Jenkins, T. A., Nguyen, J. C., Polglaze, K. E., & Bertrand, P. P. (2016). Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis. Nutrients, 8(1), 56.