Psychotic Depression - PsychDB

Last edited on April 30, 2020

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Psychotic Depression

Psychotic Depression (depression with psychotic features) requires the treatment of the underlying mood disorder.

Perera, J. K., Rosenblat, J. D., & Flint, A. J. (2017). Dementia with Lewy bodies presenting as psychotic depression. Australian & New Zealand Journal of Psychiatry, 51(11), 1160-1161.

Treatment with olanzapine plus sertraline has been shown to be efficacious.^[1]

Bingham, K. S., Rothschild, A. J., Mulsant, B. H., Whyte, E. M., Meyers, B. S., Banerjee, S., ... & Flint, A. J. (2017). The Association of Baseline Suicidality With Treatment Outcome in Psychotic Depression. The Journal of clinical psychiatry, 78(8), 1149-1154.
Rothschild, A. J. (2013). Challenges in the treatment of major depressive disorder with psychotic features. Schizophrenia bulletin, 39(4), 787-796.

¹⁾ Meyers, B. S., Flint, A. J., Rothschild, A. J., Mulsant, B. H., Whyte, E. M., Peasley-Miklus, C., ... & Heo, M. (2009). A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD). Archives of general psychiatry, 66(8), 838-847.