Daridorexant (Quviviq)

Daridorexant (Trade name: Quviviq) is a dual orexin receptor antagonist (DORA) used in the treatment of insomnia disorder.

Pharmacokinetics of Daridorexant

Daridorexant: Cytochrome P450 Metabolism

Substrate of (Metabolized by)

Dosing for Daridorexant

Starting 25 mg PO daily
Maximum 50 mg PO daily
  • Daridorexant comes in
  • Daridorexant, like all DORAs, have a theoretical risk for abuse.[1][2]
    • Patients with a history of abuse or addiction may be at increased risk for abuse and addiction to DORAs and should be followed carefully