Biphentin® (methylphenidate)

Biphentin® (methylphenidate) is a stimulant medication in the methylphenidate class used primarily in the treatment of attention-deficit/hyperactivity disorder (ADHD).

  • Two “pulses” of methylphenidate are released (each pulse lasts about 4-5 hours)
    • Immediate release pulse is about 40% of the drug
    • Controlled release is about the other 60%
  • Has a multi-layer release mechanism
  • Purportedly lasts 10-12 hours, but more likely 8-10 hours
  • Formulations: 10, 15, 20, 30, 40, 50, 60, 80mg caps
  • Starting dose: 10 to 20mg qAM
  • Titration: ­increase by 5-10mg qWeekly
  • Maximum dose: 60 mg in children/adolescents, 80 mg in adults
  • Called “Bi”-phentin because it mimics “BI”D Ritalin (methylphenidate)
  • High abuse potential!
  • Capsules may be opened up and the beads inside sprinkled on soft foods (e.g. — apple sauce, yogurt, ice cream)