Biphentin® (methylphenidate)

Biphentin® (methylphenidate) is a stimulant medication in the methylphenidate class used primarily in the treatment of attention-deficit/hyperactivity disorder (ADHD).

• Two “pulses” of methylphenidate are released (each pulse lasts about 4-5 hours)
  • Immediate release pulse is about 40% of the drug
  • Controlled release is about the other 60%
• Has a multi-layer release mechanism
• Purportedly lasts 10-12 hours, but more likely 8-10 hours

• Formulations: 10, 15, 20, 30, 40, 50, 60, 80mg caps
• Starting dose: 10 to 20mg qAM
• Titration: ­increase by 5-10mg qWeekly
• Maximum dose: 60 mg in children/adolescents, 80 mg in adults

• Called “Bi”-phentin because it mimics “BI”D Ritalin (methylphenidate)
• High abuse potential!
• Capsules may be opened up and the beads inside sprinkled on soft foods (e.g. — apple sauce, yogurt, ice cream)