Methylphenidate

Methylphenidate (Tradenames: Ritalin, Biphentin, Concerta) is a central nervous system (CNS) stimulant of the phenethylamine and piperidine class used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

There are many different formulations of methylphenidate.

Formulations

Methylphenidate-based Psychostimulants

Adapted from Annick Vincent, MD (http://www.attentiondeficit-info.com)
Brand (%Immediate/%Delayed) Duration Formulations Starting Dose Titration Notes
Ritalin (100/0) 3-4 hours 5 (generic), 10, 20mg tabs 5mg BID to TID (Adults QID) Increase by 5mg qWeekly, (max dose: 60mg, all ages) Can be crushed
Biphentin (40/60) 10-12 hours 10, 15, 20, 30, 40, 50, 60, 80mg caps 10-20mg qAM Increase by 5-10mg qWeekly, (max dose: 60mg in children/adolescents, 80mg in adults) Capsules can be opened and sprinkled as granules
Concerta (22/78) 12 hours 18, 27, 36, 54mg tabs 18mg qAM Increase by 9-18mg qWeekly, (max dose: 54mg in children/adolescents, 72mg in adults) Must be swallowed whole
Foquest (20/80) 16 hours 25, 35, 45, 55, 70,
85, 100mg caps
25mg qAM Increase by 10-15mg q5 days, (max dose: 100mg in adults) Capsules can be opened and sprinkled as granules