Table of Contents

Lurasidone (Latuda)

Primer

Pharmacokinetics

Pharmacokinetics of Lurasidone

Lurasidone: Cytochrome P450 Metabolism

Substrate of (Metabolized by)
Induces
Inhibits

Pharmacodynamics

Mechanism of Action

Toxicity

Indications

Dosing

Dosing for Lurasidone

Starting The recommended dose is 40-80 mg given once daily, with no titration needed.
Lurasidone must be taken with a meal/food with at least 350 calories (or else its absorption is reduced by 50%).[2]
Titration No titration needed, but can be increased.
Maximum 80mg PO daily (studies have gone up to 120mg with no difference in improvement)
Taper Tapering/Switching Antipsychotics

Formulations

Monitoring

Contraindications

Absolute

Relative

Drug-Drug Interactions

Side Effects

Adverse Events

Clinical Pearls

Special Populations

Geriatric

Pediatric

Obstetric and Fetal

Medically Ill

Resources