- Last edited on February 19, 2021
Desvenlafaxine (Pristiq)
Primer
Desvenlafaxine (Trade name: Pristiq) is an antidepressant in the serotonin norepinephrine reuptake inhibitor (SNRI) class used in the treatment of major depressive disorder.
Dosing
- Starting dose: 50mg
- Max dose: 100mg
Pearls
- The elimination of desvenlafaxine is independent of CYP2D6 (unlike venlafaxine), which may be a potential advantage over venlafaxine for some patients in terms of drug–drug interactions and tolerability