Doxepin (Sinequan)

  • Half-life: 3.5 hours
  • Insomnia (middle insomnia, doses of 3 to 6 mg qHS in Canada)[1]
  • Doxepin has prominent histaminergic effects, and NO anticholinergic effects, which makes it a good sleep aid
  • Best used for the treatment of maintenance insomnia, not initial insomnia