- Last edited on December 6, 2022
Imipramine (Tofranil)
Primer
Dosing
- Starting dose 10 mg p.o. q.h.s. Can be further titrated up by 10 mg every 14 days up to a maximum dose of 50 mg daily, depending on tolerability.
Side Effects
- Sleepiness, dry mouth, and nausea.
Pharmacokinetics
- Desipramine is a metabolite of imipramine.